A case of trisomy-G with a simultaneous balanced D-D translocation
نویسندگان
چکیده
منابع مشابه
Balanced Reciprocal Translocation in A Case of Recurrent Miscarriage
Reciprocal translocation carriers have reduced fertility, increased risk of spontaneous abortion or unbalanced karyotype in their offspring. Here, we report the inheritance of a translocation between chromosomes 12 and 16 in a family with a history of five consecutive blighted ova and an offspring with three cell lines of different genotypes. We assessed parental karyotypes and identified a het...
متن کاملDouble autosomal trisomy (trisomy D+G) with mosaicism.
The patient, a male, the seventh child of a 37-year-old father and a 34-year-old Caucasian mother, was the product of a pregnancy complicated by massive polyhydramnios. The mother previously had had two miscarriages. During the present pregnancy she had not had any infections or X-irradiation. There was no family history of congenital malformations, mental retardation, leukaemia, autoimmune dis...
متن کاملDown's syndrome with a familial D/D reciprocal translocation and a G/G chromosome.
The presence of a translocation between two chromosomes in the I3-I5 (D) group does not usually give rise to any phenotypical abnormality and may be relatively common in the population (Hamerton, Giannelli, and Carter, I963). Such translocations have, however, been reported in a patient with XXY Klinefelter's syndrome (Lejeune, Turpin, and DeCourt, i960), and Hamerton et al. (I963) describe a f...
متن کاملA family with D-D translocation.
Balanced D/D translocation carriers appear to be normal in most instances (Court-Brown et al., 1966; Giannelli and Howlett, 1966). In some cases, however, a variety ofcongenital malformations has been reported, such as Klinefelter's syndrome (Lejeune, Turpin, and Decourt, 1960), little secondary sex development (Walker and Harris, 1962), malformation of the spine (de Grouchy et al., 1963), arre...
متن کاملTranslocation and trisomic Down's syndrome in a family with a familial D-G translocation.
The reports on familial Down's syndrome (mongolism) date in the medical literature from the 20th years of this century. Familial Down's syndrome is now well-described event but relatively rare. Penrose states that pairs of affected sibs appear about once for every 100 single cases of mongolism collected at random (quoted by Soltan et al. 1964). About two-thirds of the mongoloids are close relat...
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ژورنال
عنوان ژورنال: Hereditas
سال: 2009
ISSN: 0018-0661
DOI: 10.1111/j.1601-5223.1974.tb01359.x